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Hierarchical looping of zigzag nucleosome chains in metaphase chromosomes
The architecture of higher-order chromatin in eukaryotic cell nuclei is largely unknown. Here, we use electron microscopy-assisted nucleosome interaction capture (EMANIC) cross-linking experiments in combination with mesoscale chromatin modeling of 96-nucleosome arrays to investigate the internal or...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747710/ https://ncbi.nlm.nih.gov/pubmed/26787893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518280113 |
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