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Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification
Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation or other posttranslational modifications of target proteins to control their function. Recently, we have shown that Fic enzymes are autoinhibited by an α-helix (α(inh)) that partly obstructs the active site. For the sing...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747691/ https://ncbi.nlm.nih.gov/pubmed/26787847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516930113 |
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