Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling

The role of death receptor 5 (DR5), a well-known cell surface pro-apoptotic protein, in the negative regulation of invasion and metastasis of human cancer cells and the underlying mechanisms are largely unknown and were hence the focus of this study. In this report, we have demonstrated that DR5 fun...

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Publicado en:Oncotarget
Autores principales: Oh, You-Take, Yue, Ping, Wang, Dongsheng, Tong, Jing-Shan, Chen, Zhuo G., Khuri, Fadlo R., Sun, Shi-Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747408/
https://ncbi.nlm.nih.gov/pubmed/26510914
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