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IL-32θ gene expression in acute myeloid leukemia suppresses TNF-α production

The proinflammatory cytokine TNF-α is highly expressed in patients with acute myeloid leukemia (AML) and has been demonstrated to induce rapid proliferation of leukemic blasts. Thus suppressing the production of TNF-α is important because TNF-α can auto-regulate own expression through activation of...

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Pubblicato in:Oncotarget
Autori principali: Kim, Man Sub, Kang, Jeong-Woo, Jeon, Jae-Sik, Kim, Jae Kyung, Kim, Jong Wan, Hong, Jintae, Yoon, Do-Young
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747366/
https://ncbi.nlm.nih.gov/pubmed/26516703
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