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IL-32θ inhibits monocytic differentiation of leukemia cells by attenuating expression of transcription factor PU.1
PU.1 is a key transcription factor regulating the myeloid differentiation. PU.1-induced monocytic differentiation into macrophage is also important for blood cancer development. Therefore, we chose THP-1 monocytic leukemia cells to investigate the function of a recently discovered IL-32θ. Genetic an...
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| Vydáno v: | Oncotarget |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414198/ https://ncbi.nlm.nih.gov/pubmed/25726525 |
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