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Inhibition of IL-13 and IL-13Rα2 Expression by IL-32θ in Human Monocytic Cells Requires PKCδ and STAT3 Association

Interleukin (IL)-32θ, a newly identified IL-32 isoform, has been reported to exert pro-inflammatory effects through the association with protein kinase C delta (PKCδ). In this study, we further examined the effects of IL-32θ on IL-13 and IL-13Rα2 expression and the related mechanism in THP-1 cells....

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pham, Thu-Huyen, Bak, Yesol, Oh, Jae-Wook, Hong, Jingi, Lee, Seungyeoun, Hong, Jin Tae, Yoon, Do-Young
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514684/
https://ncbi.nlm.nih.gov/pubmed/31010051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20081949
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