Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways

In children with hepatocellular carcinoma (pHCC) the 5-year overall survival rate is poor. Effects of cytostatic therapies such as cisplatin and doxorubicin are limited due to chemoresistance and tumor relapse. In adult HCC, several antitumor properties are described for the use of curcumin. Curcumi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bortel, Nicola, Armeanu-Ebinger, Sorin, Schmid, Evi, Kirchner, Bettina, Frank, Jan, Kocher, Alexa, Schiborr, Christina, Warmann, Steven, Fuchs, Jörg, Ellerkamp, Verena
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747361/
https://ncbi.nlm.nih.gov/pubmed/26515460
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