Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways

In children with hepatocellular carcinoma (pHCC) the 5-year overall survival rate is poor. Effects of cytostatic therapies such as cisplatin and doxorubicin are limited due to chemoresistance and tumor relapse. In adult HCC, several antitumor properties are described for the use of curcumin. Curcumi...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Bortel, Nicola, Armeanu-Ebinger, Sorin, Schmid, Evi, Kirchner, Bettina, Frank, Jan, Kocher, Alexa, Schiborr, Christina, Warmann, Steven, Fuchs, Jörg, Ellerkamp, Verena
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747361/
https://ncbi.nlm.nih.gov/pubmed/26515460
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