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ANTIGEN- AND CYTOKINE-DRIVEN ACCUMULATION OF REGULATORY T CELLS IN VISCERAL ADIPOSE TISSUE OF LEAN MICE

A unique population of Foxp3(+)CD4(+) regulatory T (Treg) cells, with a distinct transcriptome and antigen-receptor repertoire, resides in visceral adipose tissue (VAT) of lean individuals. These cells regulate local inflammation and both local and systemic metabolic indices. Here we focus on expans...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Metab
Hauptverfasser: Kolodin, Dmitriy, van Panhuys, Nicolas, Li, Chaoran, Magnuson, Angela M., Cipolletta, Daniela, Miller, Christine M., Wagers, Amy, Germain, Ronald N., Benoist, Christophe, Mathis, Diane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747251/
https://ncbi.nlm.nih.gov/pubmed/25863247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.03.005
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