Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance

Ras is aberrantly activated in many cancers and active DNA demethylation plays a fundamental role to establish DNA methylation pattern which is of importance to cancer development. However, it was unknown whether and how Ras regulate DNA demethylation during carcinogenesis. Here we found that Ras do...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Jie, Shen, Qi, Lu, Haiqi, Jiang, Zhinong, Xu, Wenxia, Feng, Lifeng, Li, Ling, Wang, Xian, Cai, Xiujun, Jin, Hongchuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747204/
https://ncbi.nlm.nih.gov/pubmed/26544625
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