Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance

Ras is aberrantly activated in many cancers and active DNA demethylation plays a fundamental role to establish DNA methylation pattern which is of importance to cancer development. However, it was unknown whether and how Ras regulate DNA demethylation during carcinogenesis. Here we found that Ras do...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Sun, Jie, Shen, Qi, Lu, Haiqi, Jiang, Zhinong, Xu, Wenxia, Feng, Lifeng, Li, Ling, Wang, Xian, Cai, Xiujun, Jin, Hongchuan
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747204/
https://ncbi.nlm.nih.gov/pubmed/26544625
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki