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5-Fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits
Despite marked tumor shrinkage after 5-FU treatment, the frequency of colon cancer relapse indicates that a fraction of tumor cells survives treatment causing tumor recurrence. The majority of cancer cells divert metabolites into anabolic pathways through Warburg behavior giving an advantage in term...
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Publicado no: | Oncotarget |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747183/ https://ncbi.nlm.nih.gov/pubmed/26527315 |
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