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Decoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chain

Otto Warburg observed that cancer cells derived their energy from aerobic glycolysis by converting glucose to lactate. This mechanism is in opposition to the higher energy requirements of cancer cells because oxidative phosphorylation (OxPhos) produces more ATP from glucose. Warburg hypothesized tha...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Garcia-Heredia, Jose M., Carnero, Amancio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747175/
https://ncbi.nlm.nih.gov/pubmed/26462158
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