Mitochondrial DNA mutations and respiratory chain dysfunction in idiopathic and connective tissue disease-related lung fibrosis

Reactive oxygen species (ROS) are implicated in the aetiology of interstitial lung disease (ILD). We investigated the role of large-scale somatically acquired mutations in mitochondrial DNA (mtDNA) and consecutive respiratory chain dysfunction as a trigger of ROS-formation and lung fibrosis. Mitocho...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jaeger, Veronika K., Lebrecht, Dirk, Nicholson, Andrew G., Wells, Athol, Bhayani, Harshil, Gazdhar, Amiq, Tamm, Michael, Venhoff, Nils, Geiser, Thomas, Walker, Ulrich A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445113/
https://ncbi.nlm.nih.gov/pubmed/30940853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41933-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados