VE1 immunohistochemistry predicts BRAF V600E mutation status and clinical outcome in colorectal cancer

AIM: VE1 is a monoclonal antibody detecting mutant BRAF(V600E) protein by immunohistochemistry. Here we aim to determine the inter-observer agreement and concordance of VE1 with mutational status, investigate heterogeneity in colorectal cancers and metastases and determine the prognostic effect of V...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Schafroth, Christian, Galván, José A., Centeno, Irene, Koelzer, Viktor H., Dawson, Heather E., Sokol, Lena, Rieger, Gregor, Berger, Martin D., Hädrich, Marion, Rosenberg, Robert, Nitsche, Ulrich, Schnüriger, Beat, Langer, Rupert, Inderbitzin, Daniel, Lugli, Alessandro, Zlobec, Inti
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747166/
https://ncbi.nlm.nih.gov/pubmed/26496026
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