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Unique genetic and epigenetic mechanisms driving signatures of paediatric diffuse high-grade glioma
Diffuse high-grade gliomas (HGGs) of childhood are a devastating spectrum of disease with no effective cures. The two-year survival for paediatric HGG ranges from 30%, for tumours arising in the cerebral cortex, to less than 10% for diffuse intrinsic pontine gliomas (DIPGs), which arise in the brain...
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| 出版年: | Nat Rev Cancer |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747023/ https://ncbi.nlm.nih.gov/pubmed/25230881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3811 |
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