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Emerging Functions of Histone H3 Mutations in Paediatric Diffuse High-Grade Gliomas
Paediatric diffuse high grade gliomas are rare, but deadly tumours. The discovery of recurrent mutations in the tail of histone H3, changing lysine 27 to methionine, or glycine 34 to arginine or valine, has illuminated a critical role for epigenetic dysregulation in the aetiology of childhood glioma...
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| Publié dans: | Neuropathol Appl Neurobiol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7174136/ https://ncbi.nlm.nih.gov/pubmed/31859390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12591 |
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