Platelet activation independent of pulmonary inflammation contributes to diesel exhaust particulate-induced promotion of arterial thrombosis

BACKGROUND: Accelerated thrombus formation induced by exposure to combustion-derived air pollution has been linked to alterations in endogenous fibrinolysis and platelet activation in response to pulmonary and systemic inflammation. We hypothesised that mechanisms independent of inflammation contrib...

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Bibliografiske detaljer
Udgivet i:Part Fibre Toxicol
Main Authors: Tabor, Caroline M., Shaw, Catherine A., Robertson, Sarah, Miller, Mark R., Duffin, Rodger, Donaldson, Ken, Newby, David E., Hadoke, Patrick W. F.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746929/
https://ncbi.nlm.nih.gov/pubmed/26857113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-016-0116-x
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