Diesel exhaust particulate induces pulmonary and systemic inflammation in rats without impairing endothelial function ex vivo or in vivo

BACKGROUND: Inhalation of diesel exhaust impairs vascular function in man, by a mechanism that has yet to be fully established. We hypothesised that pulmonary exposure to diesel exhaust particles (DEP) would cause endothelial dysfunction in rats as a consequence of pulmonary and systemic inflammatio...

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Detalhes bibliográficos
Main Authors: Robertson, Sarah, Gray, Gillian A, Duffin, Rodger, McLean, Steven G, Shaw, Catherine A, Hadoke, Patrick WF, Newby, David E, Miller, Mark R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361483/
https://ncbi.nlm.nih.gov/pubmed/22480168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-8977-9-9
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