Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph(+) leukemia

BACKGROUND: Proteostasis is defined by the orchestrated control of anabolic and catabolic protein pathways. Disruption of proteostasis results in cell stress and adaptation to proteostasis imbalance is mediated by adaptive pathways such as the Heat Shock Response (including heat-shock proteins) or t...

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Dades bibliogràfiques
Publicat a:Exp Hematol Oncol
Autors principals: Vieri, Margherita, Geng, Huimin, Patterson, John B., Panse, Jens, Wilop, Stefan, Samali, Afshin, Chevet, Eric, Masouleh, Behzad Kharabi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Rapid Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746784/
https://ncbi.nlm.nih.gov/pubmed/26862466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0034-5
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