A second transcriptionally active DNA-binding site for the Wilms tumor gene product, WT1.
The putative Wilms tumor suppressor gene, wt1, encodes a zinc-finger protein that binds to the DNA sequence 5'-GCGGGGGCG-3'. We previously reported that WT1 has separable domains that function either to activate or suppress transcription. We now have identified a second WT1 binding sequence (5'-TCCT...
Збережено в:
| Опубліковано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
National Academy of Sciences
1993
|
| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8896 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|