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Zinc finger point mutations within the WT1 gene in Wilms tumor patients.

A proposed Wilms tumor gene, WT1, which encodes a zinc finger protein, has previously been isolated from human chromosome 11p13. Chemical mismatch cleavage analysis was used to identify point mutations in the zinc finger region of this gene in a series of 32 Wilms tumors. Two exonic single base chan...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Little, M H, Prosser, J, Condie, A, Smith, P J, Van Heyningen, V, Hastie, N D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49173/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1317572/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4791
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