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Zinc finger point mutations within the WT1 gene in Wilms tumor patients.

A proposed Wilms tumor gene, WT1, which encodes a zinc finger protein, has previously been isolated from human chromosome 11p13. Chemical mismatch cleavage analysis was used to identify point mutations in the zinc finger region of this gene in a series of 32 Wilms tumors. Two exonic single base chan...

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Autors principals: Little, M H, Prosser, J, Condie, A, Smith, P J, Van Heyningen, V, Hastie, N D
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49173/
https://ncbi.nlm.nih.gov/pubmed/1317572
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