One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system

Pig shows multiple superior characteristics in anatomy, physiology, and genome that have made this species to be more suitable models for human diseases, especially for neurodegenerative diseases, because they have similar cerebral convolutions compared with human neocortex. Recently, CRISPR/Cas9 sy...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Wang, Xianlong, Cao, Chunwei, Huang, Jiaojiao, Yao, Jing, Hai, Tang, Zheng, Qiantao, Wang, Xiao, Zhang, Hongyong, Qin, Guosong, Cheng, Jinbo, Wang, Yanfang, Yuan, Zengqiang, Zhou, Qi, Wang, Hongmei, Zhao, Jianguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746670/
https://ncbi.nlm.nih.gov/pubmed/26857844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20620
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