One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system

Pig shows multiple superior characteristics in anatomy, physiology, and genome that have made this species to be more suitable models for human diseases, especially for neurodegenerative diseases, because they have similar cerebral convolutions compared with human neocortex. Recently, CRISPR/Cas9 sy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Xianlong, Cao, Chunwei, Huang, Jiaojiao, Yao, Jing, Hai, Tang, Zheng, Qiantao, Wang, Xiao, Zhang, Hongyong, Qin, Guosong, Cheng, Jinbo, Wang, Yanfang, Yuan, Zengqiang, Zhou, Qi, Wang, Hongmei, Zhao, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746670/
https://ncbi.nlm.nih.gov/pubmed/26857844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20620
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