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Characterization of an oncolytic adenovirus vector constructed to target the cMet receptor
The cMet receptor is a homodimer with tyrosine kinase activity. Upon stimulation with its ligand, hepatocyte growth factor (HGF), the receptor mediates wide physiologic actions. The HGF-cMet signaling pathway is dysregulated in many cancers, which makes cMet an important target for novel therapeutic...
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| Pubblicato in: | Oncolytic Virother |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746000/ https://ncbi.nlm.nih.gov/pubmed/26866014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S87369 |
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