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Reciprocal Control of Osteogenic and Adipogenic Differentiation by ERK/MAP Kinase Phosphorylation of Runx2 and PPARγ Transcription Factors

In many skeletal diseases, including osteoporosis and disuse osteopenia, defective osteoblast differentiation is associated with increased marrow adipogenesis. The relative activity of two transcription factors, RUNX2 and PPARγ, controls whether a mesenchymal cell will differentiate into an osteobla...

詳細記述

保存先:
書誌詳細
出版年:J Cell Physiol
主要な著者: GE, CHUNXI, CAWTHORN, WILLIAM P., LI, YAN, ZHAO, GUISHENG, MACDOUGALD, ORMOND A., FRANCESCHI, RENNY T.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745986/
https://ncbi.nlm.nih.gov/pubmed/26206105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25102
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