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Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling

The activation status of a set of pro-oncogenic tyrosine kinases in ovarian cancer patient samples was analyzed to define potential therapeutic targets. Frequent activation of HER family receptor tyrosine kinases, especially HER2, was observed. Studies in ovarian cancer cell lines confirmed the acti...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Montero, Juan Carlos, García-Alonso, Sara, Ocaña, Alberto, Pandiella, Atanasio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745781/
https://ncbi.nlm.nih.gov/pubmed/26336133
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