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Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling

The activation status of a set of pro-oncogenic tyrosine kinases in ovarian cancer patient samples was analyzed to define potential therapeutic targets. Frequent activation of HER family receptor tyrosine kinases, especially HER2, was observed. Studies in ovarian cancer cell lines confirmed the acti...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Montero, Juan Carlos, García-Alonso, Sara, Ocaña, Alberto, Pandiella, Atanasio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745781/
https://ncbi.nlm.nih.gov/pubmed/26336133
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