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Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling

The activation status of a set of pro-oncogenic tyrosine kinases in ovarian cancer patient samples was analyzed to define potential therapeutic targets. Frequent activation of HER family receptor tyrosine kinases, especially HER2, was observed. Studies in ovarian cancer cell lines confirmed the acti...

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Vydáno v:Oncotarget
Hlavní autoři: Montero, Juan Carlos, García-Alonso, Sara, Ocaña, Alberto, Pandiella, Atanasio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745781/
https://ncbi.nlm.nih.gov/pubmed/26336133
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