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Identification of therapeutic targets in ovarian cancer through active tyrosine kinase profiling

The activation status of a set of pro-oncogenic tyrosine kinases in ovarian cancer patient samples was analyzed to define potential therapeutic targets. Frequent activation of HER family receptor tyrosine kinases, especially HER2, was observed. Studies in ovarian cancer cell lines confirmed the acti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Montero, Juan Carlos, García-Alonso, Sara, Ocaña, Alberto, Pandiella, Atanasio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745781/
https://ncbi.nlm.nih.gov/pubmed/26336133
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