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HBV preS2 promotes the expression of TAZ via miRNA-338-3p to enhance the tumorigenesis of hepatocellular carcinoma

Transactivators encoded by HBV, including HBx and preS2, play critical role in hepatocellular carcinoma (HCC). YAP, a downstream effector of the Hippo pathway, is involved in hepatocarcinogenesis mediated by HBx. Here, we investigated whether preS2, another transactivator encoded by HBV, regulates t...

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Publicat a:Oncotarget
Autors principals: Liu, Peng, Zhang, Hualin, Liang, Xiaohong, Ma, Hongxin, Luan, Fang, Wang, Bo, Bai, Fuxiang, Gao, Lifen, Ma, Chunhong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745710/
https://ncbi.nlm.nih.gov/pubmed/26315112
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