Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment

BACKGROUND: Hepatitis B virus (HBV), because of its error-prone viral polymerase, has a high mutation rate leading to widespread substitutions, deletions, and insertions in the HBV genome. Deletions may significantly change viral biological features complicating the progression of liver diseases. Ho...

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Autores principales: Zhang, Dake, Dong, Peiling, Zhang, Ke, Deng, Libin, Bach, Christian, Chen, Wei, Li, Feifei, Protzer, Ulrike, Ding, Huiguo, Zeng, Changqing
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549285/
https://ncbi.nlm.nih.gov/pubmed/23272650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-307
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