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Prevalent HBV point mutations and mutation combinations at BCP/preC region and their association with liver disease progression

BACKGROUND: Mutations in the basic core promoter (BCP) and its adjacent precore (preC) region in HBV genome are common in chronic hepatitis B patients. However, the patterns of mutation combinations in these two regions during chronic infection are less understood. This study focused on single base...

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Main Authors: Zhang, Dake, Ma, Sufang, Zhang, Xin, Zhao, Hanqing, Ding, Huiguo, Zeng, Changqing
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949759/
https://ncbi.nlm.nih.gov/pubmed/20846420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-271
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