Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism

Our previous studies have shown that loss of miR-200b enhances the invasiveness of esophageal squamous cell carcinoma (ESCC) cells. However, whether the miR-200-ZEB1/2-E-cadherin regulatory cascade, a master regulator of epithelial-to-mesenchymal transition (EMT), is involved in the regulation of ES...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Hai-Feng, Alshareef, Abdulraheem, Wu, Chengsheng, Li, Shang, Jiao, Ji-Wei, Cao, Hui-Hui, Lai, Raymond, Xu, Li-Yan, Li, En-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745703/
https://ncbi.nlm.nih.gov/pubmed/26334393
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