A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation

Developing thymocytes require pre-TCR signalling to differentiate from CD4−CD8− double negative to CD4+CD8+ double positive cell. Here we followed the transcriptional response to pre-TCR signalling in a synchronised population of differentiating double negative thymocytes. This time series analysis...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Sahni, Hemant, Ross, Susan, Barbarulo, Alessandro, Solanki, Anisha, Lau, Ching-In, Furmanski, Anna, Saldaña, José Ignacio, Ono, Masahiro, Hubank, Mike, Barenco, Martino, Cromp­ton, Tessa
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper: Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745683/
https://ncbi.nlm.nih.gov/pubmed/26415229
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