Possible Protective Effect of Diacerein on Doxorubicin-Induced Nephrotoxicity in Rats

Nephrotoxicity is one of the limiting factors for using doxorubicin (DOX). Interleukin 1 has major role in DOX-induced nephrotoxicity, so we investigated the effect of interleukin 1 receptor antagonist diacerein (DIA) on DOX-induced nephrotoxicity. DIA (25 and 50 mg/kg/day) was administered orally t...

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Publicat a:J Toxicol
Autors principals: Refaie, Marwa M. M., Amin, Entesar F., El-Tahawy, Nashwa F., Abdelrahman, Aly M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745331/
https://ncbi.nlm.nih.gov/pubmed/26904117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9507563
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