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Effect of Coenzyme-Q10 on Doxorubicin-Induced Nephrotoxicity in Rats

Nephrotoxicity is one of the limiting factors for using doxorubicin (Dox) as an anticancer chemotherapeutic. Here, we investigated possible protective effect of coenzyme-Q10 (CoQ10) on Dox-induced nephrotoxicity and the mechanisms involved. Two doses (10 and 100 mg/kg) of CoQ10 were administered ora...

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Détails bibliographiques
Auteurs principaux: El-Sheikh, Azza A. K., Morsy, Mohamed A., Mahmoud, Marwa M., Rifaai, Rehab A., Abdelrahman, Aly M.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533995/
https://ncbi.nlm.nih.gov/pubmed/23346106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/981461
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