The Protective Effects of Isoliquiritigenin and Glycyrrhetinic Acid against Triptolide-Induced Oxidative Stress in HepG2 Cells Involve Nrf2 Activation

Triptolide (TP), an active ingredient of Tripterygium wilfordii Hook f., possesses a wide range of biological activities. Oxidative stress likely plays a role in TP-induced hepatotoxicity. Isoliquiritigenin (ISL) and glycyrrhetinic acid (GA) are potent hepatoprotection agents. The aim of the present...

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Vydáno v:Evid Based Complement Alternat Med
Hlavní autoři: Cao, Ling-Juan, Li, Huan-De, Yan, Miao, Li, Zhi-Hua, Gong, Hui, Jiang, Pei, Deng, Yang, Fang, Ping-Fei, Zhang, Bi-Kui
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745288/
https://ncbi.nlm.nih.gov/pubmed/26904149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8912184
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