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Transgenic mouse model of malignant skin melanoma.

Tyr-SV40E transgenic mice are specifically susceptible to melanoma due to expression of the oncogene in pigment cells. Mice of the more susceptible lines die young of early-onset eye melanomas, when skin melanomas are still infrequent and benign. To surmount this obstacle, skin from donors of two hi...

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Autors principals: Mintz, B, Silvers, W K
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47451/
https://ncbi.nlm.nih.gov/pubmed/8415613
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