Transgenic mouse model of malignant skin melanoma.
Tyr-SV40E transgenic mice are specifically susceptible to melanoma due to expression of the oncogene in pigment cells. Mice of the more susceptible lines die young of early-onset eye melanomas, when skin melanomas are still infrequent and benign. To surmount this obstacle, skin from donors of two hi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47451/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8817 |
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