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Transgenic mouse model of malignant skin melanoma.

Tyr-SV40E transgenic mice are specifically susceptible to melanoma due to expression of the oncogene in pigment cells. Mice of the more susceptible lines die young of early-onset eye melanomas, when skin melanomas are still infrequent and benign. To surmount this obstacle, skin from donors of two hi...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Mintz, B, Silvers, W K
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1993
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8415613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.19.8817
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