A perfusion bioreactor system efficiently generates cell‐loaded bone substitute materials for addressing critical size bone defects

Critical size bone defects and non‐union fractions are still challenging to treat. Cell‐loaded bone substitutes have shown improved bone ingrowth and bone formation. However, a lack of methods for homogenously colonizing scaffolds limits the maximum volume of bone grafts. Additionally, therapy robus...

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Vydáno v:Biotechnol J
Hlavní autoři: Kleinhans, Claudia, Mohan, Ramkumar Ramani, Vacun, Gabriele, Schwarz, Thomas, Haller, Barbara, Sun, Yang, Kahlig, Alexander, Kluger, Petra, Finne‐Wistrand, Anna, Walles, Heike, Hansmann, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY‐VCH Verlag 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744951/
https://ncbi.nlm.nih.gov/pubmed/26011163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201400813
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