A perfusion bioreactor system efficiently generates cell‐loaded bone substitute materials for addressing critical size bone defects

Critical size bone defects and non‐union fractions are still challenging to treat. Cell‐loaded bone substitutes have shown improved bone ingrowth and bone formation. However, a lack of methods for homogenously colonizing scaffolds limits the maximum volume of bone grafts. Additionally, therapy robus...

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Detalhes bibliográficos
Publicado no:Biotechnol J
Main Authors: Kleinhans, Claudia, Mohan, Ramkumar Ramani, Vacun, Gabriele, Schwarz, Thomas, Haller, Barbara, Sun, Yang, Kahlig, Alexander, Kluger, Petra, Finne‐Wistrand, Anna, Walles, Heike, Hansmann, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744951/
https://ncbi.nlm.nih.gov/pubmed/26011163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201400813
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