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Optimizing the medium perfusion rate in bone tissue engineering bioreactors

There is a critical need to increase the size of bone grafts that can be cultured in vitro for use in regenerative medicine. Perfusion bioreactors have been used to improve the nutrient and gas transfer capabilities and reduce the size limitations inherent to static culture, as well as to modulate c...

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Bibliographic Details
Main Authors: Grayson, Warren L, Marolt, Darja, Bhumiratana, Sarindr, Fröhlich, Mirjam, Guo, Edward, Vunjak-Novakovic, Gordana
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077473/
https://ncbi.nlm.nih.gov/pubmed/21449028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.23024
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