Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8(+) Memory Stem Cells in Acquired Aplastic Anemia

Memory stem T cells (TSCMs) constitute a long-lived, self-renewing lymphocyte population essential for the maintenance of functional immunity. Hallmarks of autoimmune disease pathogenesis are abnormal CD4(+) and CD8(+) T cell activation. We investigated the TSCM subset in 55, 34, 43, and 5 patients...

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書誌詳細
出版年:J Immunol
主要な著者: Hosokawa, Kohei, Muranski, Pawel, Feng, Xingmin, Townsley, Danielle M., Liu, Baoying, Knickelbein, Jared, Keyvanfar, Keyvan, Dumitriu, Bogdan, Ito, Sawa, Kajigaya, Sachiko, Taylor, James G., Kaplan, Mariana J., Nussenblatt, Robert B., Barrett, A. John, O’Shea, John, Young, Neal S.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744506/
https://ncbi.nlm.nih.gov/pubmed/26764034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501739
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