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Urea transporter proteins as targets for small-molecule diuretics
Conventional diuretics such as furosemide and thiazides target salt transporters in kidney tubules, but urea transporters (UTs) have emerged as alternative targets. UTs are a family of transmembrane channels expressed in a variety of mammalian tissues, in particular the kidney. UT knockout mice and...
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| Published in: | Nat Rev Nephrol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743986/ https://ncbi.nlm.nih.gov/pubmed/25488859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneph.2014.219 |
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