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Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike
Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated by a tripartite surface spike complex, which is composed of two viral glycoprotein subunits, GP1 and GP2, and the stable signal peptide. Of t...
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Pubblicato in: | PLoS Pathog |
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Autori principali: | , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Public Library of Science
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743923/ https://ncbi.nlm.nih.gov/pubmed/26849049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005418 |
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