Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike

Lassa virus is an enveloped, bi-segmented RNA virus and the most prevalent and fatal of all Old World arenaviruses. Virus entry into the host cell is mediated by a tripartite surface spike complex, which is composed of two viral glycoprotein subunits, GP1 and GP2, and the stable signal peptide. Of t...

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Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Li, Sai, Sun, Zhaoyang, Pryce, Rhys, Parsy, Marie-Laure, Fehling, Sarah K., Schlie, Katrin, Siebert, C. Alistair, Garten, Wolfgang, Bowden, Thomas A., Strecker, Thomas, Huiskonen, Juha T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743923/
https://ncbi.nlm.nih.gov/pubmed/26849049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005418
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