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Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling

To reveal the molecular mechanisms involved in cardiac lineage determination and differentiation, we quantified the proteome of human embryonic stem cells (hESCs), cardiac progenitor cells (CPCs), and cardiomyocytes during a time course of directed differentiation by label-free quantitative proteomi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Hofsteen, Peter, Robitaille, Aaron M., Chapman, Daniel Patrick, Moon, Randall T., Murry, Charles E.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743825/
https://ncbi.nlm.nih.gov/pubmed/26755607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523930113
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