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Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling

To reveal the molecular mechanisms involved in cardiac lineage determination and differentiation, we quantified the proteome of human embryonic stem cells (hESCs), cardiac progenitor cells (CPCs), and cardiomyocytes during a time course of directed differentiation by label-free quantitative proteomi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hofsteen, Peter, Robitaille, Aaron M., Chapman, Daniel Patrick, Moon, Randall T., Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743825/
https://ncbi.nlm.nih.gov/pubmed/26755607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523930113
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