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Critical roles of G(i/o) proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels

Transient Receptor Potential Canonical (TRPC) proteins form nonselective cation channels commonly known to be activated downstream from receptors that signal through phospholipase C (PLC). Although TRPC3/C6/C7 can be directly activated by diacylglycerols produced by PLC breakdown of phosphatidylinos...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Thakur, Dhananjay P., Tian, Jin-bin, Jeon, Jaepyo, Xiong, Jian, Huang, Yu, Flockerzi, Veit, Zhu, Michael X.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743816/
https://ncbi.nlm.nih.gov/pubmed/26755577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522294113
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