The novel arylamidine T-2307 demonstrates in vitro and in vivo activity against echinocandin-resistant Candida glabrata

OBJECTIVES: Candida species are major causes of invasive mycoses in immunocompetent and immunocompromised hosts. Treatment options are limited in the setting of antifungal resistance and increased rates of echinocandin-resistant Candida glabrata have been reported. The novel arylamidine T-2307 demon...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Antimicrob Chemother
Prif Awduron: Wiederhold, Nathan P., Najvar, Laura K., Fothergill, Annette W., Bocanegra, Rosie, Olivo, Marcos, McCarthy, Dora I., Fukuda, Yoshiko, Mitsuyama, Junichi, Patterson, Thomas F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743701/
https://ncbi.nlm.nih.gov/pubmed/26620102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv398
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